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Epstein-Barr Virus (EBV) by in situ Hybridization on Paraffin
Ordering Recommendation
Use to detect Epstein-Barr virus in paraffin. Includes interpretation.
New York DOH Approval Status
Specimen Required
Tissue.
Formalin fix (10% neutral buffered formalin) and paraffin-embed tissue. Transport tissue block or 5 unstained 5 micron slides. (Min: 4 slides) Protect paraffin block and/or slides from excessive heat.
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.
Paraffin block with no tumor tissue remaining. Specimens fixed in any fixative other than 10 percent neutral buffered formalin. Decalcified specimens.
Include surgical pathology report.
If multiple specimens (blocks or slides) are sent to ARUP, they must be accompanied by one of the following: an order comment indicating that the ARUP pathologist should choose the specimen most appropriate for testing (e.g., "Choose best block"), or individual orders for each sample submitted. A Pathologist Block Selection Fee (ARUP test code 3002076) will be added to orders that utilize the first option. If multiple specimens are sent to ARUP without a request for pathologist block/slide selection or individual orders, they will be held until clarification is provided.
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Methodology
In situ hybridization (ISH)
Performed
Mon-Fri
Reported
2-5 days
Reference Interval
Negative
Interpretive Data
Refer to report
Laboratory Developed Test (LDT)
Note
Hotline History
CPT Codes
88365
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 3003235 | H and E Slide Description | |
| 3003236 | Epstein-Barr Virus (EBV) ISH Result | |
| 3003237 | EBV ISH Comment | |
| 3003240 | ISH Reference Number | |
| 3003241 | ISH Tissue Source |
Aliases
- EBER ISH
- EBV by ISH
- EBV ISH
